A Variety of Regularization problems Grace Wahba Univ of Wisconsin Statistics Abstract We review a selected class of regularization problems which balance distance to the observations with a penalty on the complexity or size of the solution. Considered are a variety of definitions of 'closeness', and several selected penalties, based on RKHS or $l_1$ norms. A class of tuning methods which generalize the Generalized Cross Validation (GCV) to distance criteria other than least squares are noted. Smoothing Spline ANOVA (SS-ANOVA) models will be described, and their use in a study selecting important important variables affecting the risk of progression of an eye disease, based on data from a demographic study. Variable/Model selection will be based on the Likelihood Basis Pursuit method described in Zhang et al, TR 1059r available via \\ {\tt http://www.stat.wisc.edu/\~{}wahba}, click on \\ "TRLIST".