                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: BEFORE   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    2      72.86666667     36.43333333     1.66    0.2092
Error                   27     593.00000000     21.96296296
Corrected Total         29     665.86666667
                  R-Square             C.V.        Root MSE        BEFORE Mean
                  0.109431         43.66273       4.6864659          10.733333
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
DRUG                     2      72.86666667     36.43333333     1.66    0.2092
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
DRUG                     2      72.86666667     36.43333333     1.66    0.2092
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: AFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    2     293.60000000    146.80000000     3.98    0.0305
Error                   27     995.10000000     36.85555556
Corrected Total         29    1288.70000000
                  R-Square             C.V.        Root MSE         AFTER Mean
                  0.227826         76.84655       6.0708777          7.9000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
DRUG                     2     293.60000000    146.80000000     3.98    0.0305
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
DRUG                     2     293.60000000    146.80000000     3.98    0.0305
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Level of        ------------BEFORE-----------     ------------AFTER------------
DRUG        N       Mean              SD              Mean              SD
A          10      9.3000000       4.76211904        5.3000000       4.64399254
B          10     10.0000000       5.24933858        6.1000000       6.15449249
C          10     12.9000000       3.95671019       12.3000000       7.14998057
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: AFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    3     871.49740304    290.49913435    18.10    0.0001
Error                   26     417.20259696     16.04625373
Corrected Total         29    1288.70000000
                  R-Square             C.V.        Root MSE         AFTER Mean
                  0.676261         50.70604       4.0057775          7.9000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
BEFORE                   1     802.94369243    802.94369243    50.04    0.0001
DRUG                     2      68.55371060     34.27685530     2.14    0.1384
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
BEFORE                   1     577.89740304    577.89740304    36.01    0.0001
DRUG                     2      68.55371060     34.27685530     2.14    0.1384
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                              Least Squares Means
            DRUG         AFTER       Std Err     Pr > |T|   LSMEAN
                        LSMEAN        LSMEAN   H0:LSMEAN=0   Number
            A        6.7149635     1.2884943        0.0001     1
            B        6.8239348     1.2724690        0.0001     2
            C       10.1611017     1.3159234        0.0001     3
                       Pr > |T| H0: LSMEAN(i)=LSMEAN(j)
                            i/j     1       2       3
                            1   .      0.9521  0.0793
                            2  0.9521   .      0.0835
                            3  0.0793  0.0835   .    
NOTE: To ensure overall protection level, only probabilities associated with 
      pre-planned comparisons should be used.
                                                 17:43 Wednesday, March 8, 1995
               Plot of AFTER*BEFORE.   Symbol is value of DRUG.
               Plot of PAFTER*BEFORE.  Symbol used is '*'.
      AFTER |
         25 +
            |
            |                                                        C
            |
            |
            |
         20 +                             C
                                                                     *
            |
            |                          C                    B
            |
            |
            |                             C
         15 +
                                                      *        *
            |                                                  B
                                                            *
            |                       A                 C
            |
                                             *
            |                                         C
                                          *
            |                                                  A
                                       *           *
         10 +                                C
                                                *
            |                 B                    B
            |                          A        A
                                 *
            |
            |
                           *           *
            |                          A
                                    *
          5 +                    C        C
            |           A     B
                              *
            |              B
                           *
            |
                        *
            |        A  B
                        *
            |        B  A  C  B
                     *
          0 +  A        B     A
            |
               *
            |
            |
            |
            |
         -5 +
            ---+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--
               3  4  5  6  7  8  9 10 11 12 13 14 15 16 17 18 19 20 21
                                       BEFORE
NOTE: 11 obs hidden.                                                           
                                                 17:43 Wednesday, March 8, 1995
               Plot of RAFTER*PAFTER.  Symbol is value of DRUG.
RAFTER |
       |
  10.0 +
       |
       |
       |                                      C
       |
   7.5 +                                    C
       |                          A
       |
       |
       |
   5.0 +                      B
       |                                      C
       |                                            B
       |
       |
   2.5 +                                                          C
       |                 A
       |
       |           A   A            A
       |
   0.0 +                B B B B
       |
       |                 A          A                 B
       |
       |                  B                A B
  -2.5 +                                        C      C
       |                      B
       |                                C              C
       |                      A                       A
       |
  -5.0 +
       |                           C
       |
       |                                      C
       |
  -7.5 +
       |
       ---+----------+----------+----------+----------+----------+----------+--
         -5          0          5         10         15         20         25
                                        PAFTER
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: AFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    2     293.60000000    146.80000000     3.98    0.0305
Error                   27     995.10000000     36.85555556
Corrected Total         29    1288.70000000
                  R-Square             C.V.        Root MSE         AFTER Mean
                  0.227826         76.84655       6.0708777          7.9000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
DRUG                     2     293.60000000    146.80000000     3.98    0.0305
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
DRUG                     2     293.60000000    146.80000000     3.98    0.0305
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: RAFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    1     514.65732879    514.65732879    29.99    0.0001
Error                   28     480.44267121     17.15866683
Corrected Total         29     995.10000000
                  R-Square             C.V.        Root MSE        RAFTER Mean
                  0.517192          9999.99       4.1423021          0.0000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
BEFORE                   1     514.65732879    514.65732879    29.99    0.0001
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
BEFORE                   1     514.65732879    514.65732879    29.99    0.0001
                                        T for H0:    Pr > |T|   Std Error of
Parameter                  Estimate    Parameter=0                Estimate
INTERCEPT              -9.436263516          -5.01     0.0001     1.88166150
BEFORE                  0.879154986           5.48     0.0001     0.16052702
                                                 17:43 Wednesday, March 8, 1995
              Plot of RAFTER*BEFORE.   Symbol is value of DRUG.
              Plot of PRAFTER*BEFORE.  Symbol used is '*'.
      RAFTER |
          15 +
             |
             |
             |
             |                                               B
             |                                                        C
          10 +
             |
                                                                      *
             |
             |                       A     C                    B
                                                                *
             |
                                                             *
             |                          C                       A
           5 +
                                                       *
             |
                                                    *
             |                             C
             |                 B        A        A  B
                                                 *
             |
                                              *
             |                          A              C
                                           *
           0 +                                         C
                                        *
             |
                                     *
             |           A
                                  *
             |                 B              C
                               *
             |        A     B
                            *
             |           B
                         *
          -5 +  A     B        A
                      *
             |           B
             |
                *
             |                    C        C
             |
             |
         -10 +
             |
             |              C
             |
             |
             |
         -15 +
             ---+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--
                3  4  5  6  7  8  9 10 11 12 13 14 15 16 17 18 19 20 21
                                        BEFORE
NOTE: 16 obs hidden.                                                           
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: AFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    1     802.94369243    802.94369243    46.28    0.0001
Error                   28     485.75630757     17.34843956
Corrected Total         29    1288.70000000
                  R-Square             C.V.        Root MSE         AFTER Mean
                  0.623065         52.72336       4.1651458          7.9000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
BEFORE                   1     802.94369243    802.94369243    46.28    0.0001
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
BEFORE                   1     802.94369243    802.94369243    46.28    0.0001
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
Class    Levels    Values
DRUG          3    A B C
PAFTER       16    10.38906688 9.290949139 -0.592110533 1.6041249499
                   11.487184622 12.585302363 13.683420104 15.879655587
                   16.977773328 19.174008811 2.7022426912 3.8003604325
                   4.8984781738 5.9965959151 7.0947136564 8.1928313977
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: RAFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    2      61.25605285     30.62802642     1.95    0.1621
Error                   27     424.50025472     15.72223166
Corrected Total         29     485.75630757
                  R-Square             C.V.        Root MSE        RAFTER Mean
                  0.126104         -9999.99       3.9651269         -0.0000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
DRUG                     2      61.25605285     30.62802642     1.95    0.1621
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
DRUG                     2      61.25605285     30.62802642     1.95    0.1621
                                                 17:43 Wednesday, March 8, 1995
              Plot of RAFTER*PAFTER.   Symbol is value of DRUG.
              Plot of MRAFTER*PAFTER.  Symbol used is '*'.
RAFTER |
       |
  12.5 +
       |
       |
       |                                        C
  10.0 +                                     C
       |
       |
       |
   7.5 +
       |                                        C
       |
       |                                  A
   5.0 +
       |                            B
       |                                                                    C
       |
   2.5 +
       |                                                          B
                                 *     *     *  *  *        *               *
       |                      A
       |            A     A
   0.0 +                                     A
       |                  B   B  B  B              C        C
       |                               C
                    *     *   *  *  *     *  *        *  *        *   *
       |                      A                             C
  -2.5 +                      B  C           A
       |                                                              B
       |                            B                 A  B
       |                                        C
  -5.0 +                            A
       |
       |                                                              A
       |
  -7.5 +
       |
       -+-------------+-------------+-------------+-------------+-------------+
       -5             0             5            10            15            20
                                        PAFTER
NOTE: 12 obs hidden.                                                           
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: AFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    3     871.49740304    290.49913435    18.10    0.0001
Error                   26     417.20259696     16.04625373
Corrected Total         29    1288.70000000
                  R-Square             C.V.        Root MSE         AFTER Mean
                  0.676261         50.70604       4.0057775          7.9000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
DRUG                     2     293.60000000    146.80000000     9.15    0.0010
BEFORE                   1     577.89740304    577.89740304    36.01    0.0001
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: AFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    3     871.49740304    290.49913435    18.10    0.0001
Error                   26     417.20259696     16.04625373
Corrected Total         29    1288.70000000
                  R-Square             C.V.        Root MSE         AFTER Mean
                  0.676261         50.70604       4.0057775          7.9000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
BEFORE                   1     802.94369243    802.94369243    50.04    0.0001
DRUG                     2      68.55371060     34.27685530     2.14    0.1384
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: AFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    3     871.49740304    290.49913435    18.10    0.0001
Error                   26     417.20259696     16.04625373
Corrected Total         29    1288.70000000
                  R-Square             C.V.        Root MSE         AFTER Mean
                  0.676261         50.70604       4.0057775          7.9000000
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
BEFORE                   1     577.89740304    577.89740304    36.01    0.0001
DRUG                     2      68.55371060     34.27685530     2.14    0.1384
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: AFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    3     882.63946368    294.21315456    18.84    0.0001
Error                   26     406.06053632     15.61771294
Corrected Total         29    1288.70000000
                  R-Square             C.V.        Root MSE         AFTER Mean
                  0.684907         50.02437       3.9519252          7.9000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
BEFORE*DRUG              3     882.63946368    294.21315456    18.84    0.0001
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
BEFORE*DRUG              3     882.63946368    294.21315456    18.84    0.0001
                                                 17:43 Wednesday, March 8, 1995
               Plot of AFTER*BEFORE.  Symbol is value of DRUG.
      AFTER |
            |
         23 +                                                        C
         22 +
         21 +
         20 +                             C
         19 +
         18 +                          C                    B
         17 +
         16 +                             C
         15 +
         14 +                                                  B
         13 +                       A                 C
         12 +                                         C
         11 +                                                  A
         10 +                                C
          9 +                 B                    B
          8 +                          A        A
          7 +
          6 +                          A
          5 +                    C        C
          4 +           A     B
          3 +              B
          2 +        A  B
          1 +        B  A  C  B
          0 +  A        B     A
            |
            ---+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--
               3  4  5  6  7  8  9 10 11 12 13 14 15 16 17 18 19 20 21
                                       BEFORE
                                                 17:43 Wednesday, March 8, 1995
                  Plot of PAFTER*BEFORE.  Symbol used is '*'.
      PAFTER |
          25 +
             |
             |
             |
             |                                                        *
             |
          20 +
             |
             |
             |
             |
             |                                         *
          15 +                                                  *
             |                                               *
             |                                                  *
             |                                *
             |
             |                             *        *
          10 +                          *
             |                                   *
             |
             |                    *
             |                          *
             |                       *
           5 +              *
             |                 *
             |              *
             |           *
             |        *
             |        *
           0 +
             |  *
             |
             |
             |
             |
          -5 +
             |
             ---+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--+--
                3  4  5  6  7  8  9 10 11 12 13 14 15 16 17 18 19 20 21
                                        BEFORE
NOTE: 10 obs hidden.
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
                            Class Level Information
                           Class    Levels    Values
                           DRUG          3    A B C
                    Number of observations in data set = 30
                                                 17:43 Wednesday, March 8, 1995
                        General Linear Models Procedure
Dependent Variable: RAFTER   
                                     Sum of            Mean
Source                  DF          Squares          Square  F Value    Pr > F
Model                    3       6.28077414      2.09359138     0.13    0.9399
Error                   26     410.92182282     15.80468549
Corrected Total         29     417.20259696
                  R-Square             C.V.        Root MSE        RAFTER Mean
                  0.015054         -9999.99       3.9755107         -0.0000000
Source                  DF        Type I SS     Mean Square  F Value    Pr > F
PAFTER*DRUG              3       6.28077414      2.09359138     0.13    0.9399
Source                  DF      Type III SS     Mean Square  F Value    Pr > F
PAFTER*DRUG              3       6.28077414      2.09359138     0.13    0.9399
                                                 17:43 Wednesday, March 8, 1995
              Plot of RAFTER*PAFTER.   Symbol is value of DRUG.
              Plot of PRAFTER*PAFTER.  Symbol used is '*'.
RAFTER |
  10.0 +
       |
       |
       |                                      C
       |
   7.5 +                                    C
       |                          A
       |
       |
       |
   5.0 +                      B
       |                                      C
       |                                            B
       |
       |
   2.5 +                                                          C
       |                 A
       |
       |           A   A            A
       |
                                             *      * *           *
   0.0 +                B B B B
                   *   **** * *    *    *   * * *      *
       |
                              *   * *
       |                 A          A                 B
                                           *
       |
                                                      *
       |                  B                A B
  -2.5 +                                        C      C
       |                      B
       |                                C              C
       |                      A                       A
       |
  -5.0 +
       |                           C
       |
       |                                      C
       |
  -7.5 +
       |
       ---+----------+----------+----------+----------+----------+----------+--
         -5          0          5         10         15         20         25
                                        PAFTER
NOTE: 8 obs hidden.                                                            
