The popular R/qtl package for gene mapping has been redeveloped for high volume, multi-parent systems genetics data as R/qtl2. This new package is still in a state of flux, so please work with us to improve. Information in this folder largely refers to extensions to R/qtl2, including a Shiny interface.

http://www.statlab.wisc.edu/shiny/qtl2shiny shows this server in action. R/qtl2shiny Screen Shots has a series of screen shots, giving examples of R/qtl2shiny in action.

For more details on use of the package, see the R/qtl2shiny package, R/qtl2shiny User Guide and R/qtl2shiny Developer Guide. This document is created by inst/scripts/qtl2shiny_index.Rmd.

See also ReclaDemo.Rmd for scripts to generate most of these summaries and figures. This uses four other packages that can be employed on their own separate from R/qtl2shiny. In particular, R/qtl2ggplot provides full capability for ggplot2 plot objects. The R/qtl2fst package transforms large, slow calc_genoprob objects central to R/qtl2 into a set of fst databases for quick access. R/qtl2pattern provides added funtionality to look at SNP patterns and other information in more detail. See each package for its own documentation.

There is another package that is more specialized and still needs documentation: R/CausalMST concerns Causal Model Selection Tests, which are used in conjunction with mediation to formally infer causal relationship between a phenotype and other phenotypes that co-map.